A Multi-Layer Functional Genomic Analysis to Understand Noncoding Genetic Variation in Lipids
- Creator: Ramdas, Shweta , Judd, Jonathan , Bhatti, Konain Fatima , Noordam, R , Mauro, P , Matteo, F , McDaid, AF , Marques-Vidal, P , Wielscher, M , Trompet, S , Sattar, N , Mollehave, LT , Munz, M , Vedantam, Sailaja , Zeng, L , Huang, J , Yang, B , Poveda, A , Kurbasic, A , Schonherr, S , Forer, L , Scholz, M , Galesloot, TE , Bradfield, JP , Winkler, Thomas W. , Ruotsalainen, SE , Daw, EW , Zmuda, JM , Mitchell, JS , Fuchsberger, C , Christensen, H , Brody, JA , Le, P , Feitosa, MF , Wojczynski, MK , Locke, Adam E. , Hemerich, D , Preuss, M , Mangino, M , Christofidou, P , Verweij, N , Benjamins, JW , Engmann, J , Noah, TL , Verma, A , Slieker, RC , Marouli, Eirini , Lo, KS , Zilhao, NR , Kleber, ME , Delgado, GE , Huo, S , Ikeda, DD , Iha, H , Yang, J , Liu, J , Demirkan, A , Zajac, Greg J. M. , Leonard, HL , Marten, J , Emmel, C , Schmidt, B , Smyth, LJ , Canadas-Garre, M , Wang, C , Nakatochi, M , Wong, A , Hutri-Kahonen, N , Wu, Kuan-Han H. , Sim, X , Xia, R , Huerta-Chagoya, A , Fernandez-Lopez, JC , Lyssenko, V , Nongmaithem, SS , Sankareswaran, A , Irvin, MR , Oldmeadow, C , Kim, H-N , Ntalla, Ioanna , Ryu, S , Timmers, PRHJ , Arbeeva, L , Dorajoo, R , Lange, LA , Prasad, G , Lores-Motta, L , Pauper, M , Long, J , Li, X , Hui, Qin , Theusch, E , Takeuchi, F , Spracklen, CN , Loukola, A , Bollepalli, S , Warner, SC , Wang, YX , Wei, WB , Nutile, T , Ruggiero, D , Klarin, Derek , Sung, YJ , Chen, S , Liu, F , Kentistou, KA , Banas, B , Morgan, A , Meidtner, K , Bielak, LF , Smith, JA , Graham, Sarah E. , Hilliard, Austin T. , Hebbar, P , Farmaki, A-E , Hofer, E , Lin, M , Concas, MP , Vaccargiu, S , van der Most, PJ , Pitkanen, N , Cade, BE , van der Laan, SW , Wang, Z , Chitrala, KN , Weiss, S , Bentley, AR , Doumatey, AP , Adeyemo, AA , Lee, JY , Petersen, ERB , Nielsen, AA , Choi, HS , Nethander, M , Xue, C , Freitag-Wolf, S , Southam, L , Rayner, NW , Wang, Carol A. , Lin, S-Y , Wang, J-S , Couture, C , Lyytikainen, L-P , Nikus, K , Cuellar-Partida, G , Thorleifsson, G , Vestergaard, H , Hidalgo, B , Giannakopoulou, O , Cai, Q , Obura, MO , van Setten, J , He, KY , Tang, H , Terzikhan, N , Shin, JH , Helgadottir, A , Jackson, RD , Reiner, AP , Martin, LW , Chen, Z , Li, L , Kawaguchi, T , Thiery, J , Bis, JC , Launer, LJ , Li, H , Gudbjartsson, DF , Nalls, MA , Raitakari, OT , Ichihara, S , Wild, SH , Nelson, CP , Campbell, H , Jager, S , Nabika, T , Al-Mulla, F , Niinikoski, H , Holm, H , Braund, PS , Kolcic, I , Kovacs, P , Giardoglou, T , Katsuya, T , de Kleijn, D , de Borst, GJ , Kim, EK , Adams, HHH , Ikram, MA , Olafsson, I , Zhu, X , Asselbergs, FW , Kraaijeveld, AO , Beulens, JWJ , Shu, X-O , Rallidis, LS , Pedersen, O , Hansen, T , Mitchell, P , Hewitt, AW , Hwang, MY , Kahonen, M , Perusse, L , Bouchard, C , Tonjes, A , Chen, Y-DI , Pennell, CE , Mori, TA , Lieb, W , Franke, A , Ohlsson, C , Han, S , Mellstrom, D , Cho, YS , Lee, H , Yuan, J-M , Koh, W-P , Rhee, SY , Woo, J-T , Heid, IM , Stark, KJ , Zimmermann, ME , Kanoni, Stavroula , Akiyama, M , Volzke, H , Homuth, G , Evans, MK , Zonderman, AB , Polasek, O , Pasterkamp, G , Hoefer, IE , Redline, S , Pahkala, K , Oldehinkel, AJ , Sakaue, S , Snieder, H , Biino, G , Schmidt, R , Schmidt, H , Bandinelli, S , Dedoussis, G , Thanaraj, TA , Peyser, PA , Kato, N , Schulze, MB , Terao, C , Girotto, G , Boger, CA , Jung, B , Joshi, PK , Bennett, DA , De Jager, PL , Lu, X , Mamakou, V , Brown, M , Caulfield, MJ , Kanai, M , Munroe, PB , Guo, X , Ciullo, M , Jonas, JB , Samani, NJ , Kaprio, J , Pajukanta, P , Tusie-Luna, T , Aguilar-Salinas, CA , Adair, LS , Zhou, W , Bechayda, SA , de Silva, HJ , Wickremasinghe, AR , Krauss, RM , Wu, J-Y , Zheng, W , den Hollander, A , Bharadwaj, D , Correa, A , Wilson, JG , Brumpton, BM , Lind, L , Heng, C-K , Nelson, AE , Golightly, YM , Wilson, JF , Penninx, B , Kim, H-L , Attia, John , Scott, RJ , Rao, DC , Rasheed, H , Arnett, DK , Walker, M , Scott, LJ , Koistinen, HA , Chandak, GR , Mercader, JM , Villalpando, CG , Orozco, L , Fornage, M , Tai, ES , Havulinna, AS , van Dam, RM , Lehtimaki, T , Chaturvedi, N , Yokota, M , Reilly, DF , McKnight, AJ , Kee, F , Jockel, K-H , McCarthy, M , Veturi, Y , Palmer, CNA , Vitart, V , Hayward, C , Simonsick, E , van Duijn, CM , Jin, Z-B , Lu, F , Hishigaki, H , Lin, X , Marz, W , Pacheco, JA , Gudnason, V , Tardif, J-C , Lettre, G , Hart, LMT , Elders, PJM , Rader, DJ , Damrauer, SM , Kumari, M , Kivimaki, M , van der Harst, P , Wang, Yuxuan , Rosenthal, EA , Spector, TD , Loos, RJF , Province, MA , Parra, EJ , Cruz, M , Psaty, BM , Brandslund, I , Pramstaller, PP , Rotimi, CN , Christensen, K , Lingren, T , Ripatti, S , Widen, E , Hakonarson, H , Grant, SFA , Kiemeney, L , de Graaf, J , Loeffler, M , Kronenberg, F , Gu, D , Erdmann, J , Feng, Q , Schunkert, H , Franks, PW , Linneberg, A , Jukema, JW , Khera, A , Mannikko, M , Jarvelin, M-R , Kutalik, Z , Francesco, C , Mook-Kanamori, DO , Kullo, IJ , van Dijk, KW , Watkins, H , Strachan, DP , Grarup, N , Sever, P , Poulter, N , Sheu, WH-H , Rotter, J , Dantoft, TM , Karpe, F , Narita, A , Neville, MJ , Timpson, NJ , Cheng, C-Y , Wong, T-Y , Khor, CC , Sabanayagam, C , Peters, A , Gieger, C , Hattersley, AT , Takayama, J , Pedersen, NL , Magnusson, PKE , Boomsma, D , de Geus, EJC , Cupples, LA , van Meurs, JBJ , Ikram, A , Ghanbari, M , Gordon-Larsen, P , Huang, W , Martin, HC , Kim, YJ , Tabara, Y , Wareham, NJ , Langenberg, C , Zeggini, E , Tuomilehto, J , Kuusisto, J , Laakso, M , Ingelsson, E , Abecasis, G , Hunt, KA , Chambers, JC , Kooner, JS , de Vries, PS , Morrison, AC , Hazelhurst, S , Ramsay, M , North, KE , Daviglus, M , Kraft, P , Martin, NG , Trivedi, B , Whitfield, JB , Abbas, S , Saleheen, D , Walters, RG , Holmes, M , Black, C , Smith, BH , Baras, A , Justice, AE , Buring, JE , Haessler, J , Ridker, PM , Chasman, D , Kooperberg, C , Tamiya, G , Yamamoto, M , van Heel, DA , Trembath, RC , Wei, W-Q , Jarvik, GP , Namjou, B , Surakka, Ida , Giulianini, F , Hayes, MG , Ritchie, MD , Jousilahti, P , Salomaa, V , Hveem, K , Asvold, BO , Kubo, M , Kamatani, Y , Okada, Y , Murakami, Y , Bradford, Y , Kim, B-J , Thorsteinsdottir, U , Stefansson, K , Zhang, J , Chen, YE , Ho, Y-L , Lynch, JA , Tsao, PS , Chang, K-M , Cho, K , Miller, JE , O'Donnell, CJ , Gaziano, JM , Wilson, P , Mohlke, KL , Frayling, TM , Hirschhorn, JN , Kathiresan, S , Boehnke, M , Grant, S , Natarajan, P , Campbell, A , Sun, Y , Morris, AP , Deloukas, P , Peloso, G , Assimes, TL , Willer, CJ , Brown, CD , Lin, K , Millwood, IY , Rasheed, A , Hindy, G , Faul, JD , Zhao, W , Wenz, Brandon , Weir, DR , Turman, C , Huang, H , Graff, M , Choudhury, A , Sengupta, D , Mahajan, A , Brown, MR , Zhang, W , Yu, K , Clarke, Shoa L. , Schmidt, EM , Pandit, A , Gustafsson, S , Yin, X , Luan, J , Zhao, J-H , Matsuda, F , Jang, H-M , Yoon, K , Medina-Gomez, C , Chesi, Alessandra , Pitsillides, A , Hottenga, JJ , Wood, AR , Ji, Y , Gao, Z , Haworth, S , Mitchell, RE , Chai, JF , Aadahl, M , Bjerregaard, AA , Wells, Andrew , Yao, J , Manichaikul, A , Lee, W-J , Hsiung, CA , Warren, HR , Ramirez, J , Bork-Jensen, J , Karhus, LL , Goel, A , Sabater-Lleal, M
- Resource Type: journal article
- Date: 2022
A Saturated Map of Common Genetic Variants Associated with Human Height
- Creator: Yengo, Loïc , Vedantam, Sailaja , Miao, Jenkai , Gustafsson, S , Haessler, J , Hansen, TF , Havulinna, AS , Haworth, SJ , He, J , Heard-Costa, N , Hebbar, P , Hindy, G , Ho, Y-LA , Arias, Joshua D. , Hofer, E , Holliday, Elizabeth , Horn, K , Hornsby, WE , Hottenga, J-J , Huang, H , Huang, J , Huerta-Chagoya, A , Huffman, JE , Hung, Y-J , Graham, Sarah E. , Huo, S , Hwang, MY , Iha, H , Ikeda, DD , Isono, M , Jackson, AU , Jager, S , Jansen, IE , Johansson, I , Jonas, JB , Mukamel, Ronen E. , Jonsson, A , Jorgensen, T , Kalafati, I-P , Kanai, M , Kanoni, S , Karhus, LL , Kasturiratne, A , Katsuya, T , Kawaguchi, T , Kember, RL , Spracklen, Cassandra N. , Kentistou, KA , Kim, H-N , Kim, YJ , Kleber, ME , Knol, MJ , Kurbasic, A , Lauzon, M , Le, P , Lea, R , Lee, J-Y , Yin, Xianyong , Leonard, HL , Li, SA , Li, X , Liang, J , Lin, H , Lin, S-Y , Liu, J , Liu, X , Lo, KS , Chen, Shyh-Huei , Long, J , Lores-Motta, L , Luan, J , Lyssenko, V , Lyytikainen, L-P , Mahajan, A , Mamakou, V , Mangino, M , Manichaikul, A , Marten, J , Ferreira, Teresa , Mattheisen, M , Mavarani, L , McDaid, AF , Meidtner, K , Melendez, TL , Mercader, JM , Milaneschi, Y , Miller, JE , Millwood, IY , Mishra, PP , Highland, Heather H. , Mitchell, RE , Mollehave, LT , Morgan, A , Mucha, S , Munz, M , Nakatochi, M , Nelson, CP , Nethander, M , Nho, CW , Nielsen, AA , Ji, Yingjie , Nolte, IM , Nongmaithem, SS , Noordam, R , Ntalla, I , Nutile, T , Pandit, A , Christofidou, P , Parna, K , Pauper, M , Petersen, ERB , Marouli, Eirini , Karaderi, Tugce , Petersen, L , Pitkanen, N , Polasek, O , Poveda, A , Preuss, MH , Pyarajan, S , Raffield, LM , Rakugi, H , Ramirez, J , Rasheed, A , Lin, K , Raven, D , Rayner, NW , Riveros, Carlos , Rohde, R , Ruggiero, D , Ruotsalainen, SE , Ryan, KA , Sabater-Lleal, M , Saxena, R , Scholz, M , Lull, K , Sendamarai, A , Shen, B , Shi, J , Shin, JH , Sidore, C , Sitlani, CM , Slieker, RKC , Smit, RAJ , Smith, A , Smith, JA , Malden, DE , Smyth, LJ , Southam, LE , Steinthorsdottir, V , Sun, L , Takeuchi, F , Tallapragada, D , Taylor, KD , Tayo, BO , Tcheandjieu, C , Terzikhan, N , Medina-Gomez, C , Tesolin, P , Teumer, A , Theusch, E , Thompson, DJ , Thorleifsson, G , Timmers, PRHJ , Trompet, S , Turman, C , Vaccargiu, S , van der Laan, SW , Machado, M , van der Most, PJ , van Klinken, JB , van Setten, J , Verma, SS , Verweij, N , Veturi, Y , Wang, Carol A. , Wang, C , Wang, L , Wang, Z , Moore, A , Warren, HR , Wei, WB , Wickremasinghe, AR , Wielscher, M , Wiggins, KL , Winsvold, BS , Wong, A , Wu, Y , Wuttke, M , Xia, R , Rueger, S , Xie, T , Yamamoto, K , Yang, J , Yao, J , Young, H , Yousri, NA , Yu, L , Zeng, L , Zhang, W , Zhang, X , Sim, X , Zhao, J-H , Zhao, W , Zhou, W , Zimmermann, ME , Zoledziewska, M , Adair, LS , Adams, HHH , Aguilar-Salinas, CA , Al-Mulla, F , Arnett, DK , Vrieze, S , Asselbergs, FW , Asvold, BO , Attia, John , Banas, B , Bandinelli, S , Bennett, DA , Bergler, T , Bharadwaj, D , Biino, G , Bisgaard, H , Sidorenko, Julia , Ahluwalia, TS , Boerwinkle, E , Boger, CA , Bonnelykke, K , Boomsma, D , Borglum, AD , Borja, JB , Bouchard, C , Bowden, DW , Brandslund, I , Brumpton, B , Akiyama, M , Buring, JE , Caulfield, MJ , Chambers, JC , Chandak, GR , Chanock, SJ , Chaturvedi, N , Chen, Y-DI , Chen, Z , Cheng, C-Y , Christophersen, IE , Allison, MA , Ciullo, M , Cole, JW , Collins, FS , Cooper, RS , Cruz, M , Cucca, F , Cupples, LA , Cutler, MJ , Damrauer, SM , Dantoft, TM , Alvarez, M , de Borst, GJ , de Groot, LCPGM , De Jager, PL , de Kleijn, DP , de Silva, HJ , Dedoussis, G , den Hollander, A , Du, S , Easton, DF , Elders, PJM , Andersen, MK , Eliassen, AH , Ellinor, PT , Elmstahl, S , Erdmann, J , Evans, MK , Fatkin, D , Feenstra, B , Feitosa, MF , Ferrucci, L , Ford, I , Ani, A , Fornage, M , Franke, A , Franks, PW , Freedman, B , Gasparini, P , Gieger, C , Girotto, G , Goddard, ME , Golightly, YM , Gonzalez-Villalpando, C , Appadurai, V , Gordon-Larsen, P , Grallert, H , Grant, SFA , Grarup, N , Griffiths, L , Gudnason, V , Haiman, C , Hakonarson, H , Hansen, T , Hartman, CA , Arbeeva, L , Hattersley, AT , Hayward, C , Heckbert, SR , Heng, C-K , Hengstenberg, C , Hewitt, AW , Hishigaki, H , Hoyng, CB , Huang, PL , Huang, W , Bhaskar, S , Hunt, SC , Hveem, K , Hypponen, E , Iacono, WG , Ichihara, S , Ikram, MA , Isasi, CR , Jackson, RD , Jarvelin, M-R , Jin, Z-B , Bielak, LF , Jockel, K-H , Joshi, PK , Jousilahti, P , Jukema, JW , Kahonen, M , Kamatani, Y , Kang, KD , Kaprio, J , Kardia, SLR , Karpe, F , Bartell, Eric , Bollepalli, S , Kato, N , Kee, F , Kessler, T , Khera, A , Khor, CC , Kiemeney, LALM , Kim, B-J , Kim, EK , Kim, H-L , Kirchhof, P , Bonnycastle, LL , Kivimaki, M , Koh, W-P , Koistinen, HA , Kolovou, GD , Kooner, JS , Kooperberg, C , Kottgen, A , Kovacs, P , Kraaijeveld, A , Kraft, P , Bork-Jensen, J , Krauss, RM , Kumari, M , Kutalik, Z , Laakso, M , Lange, LA , Langenberg, C , Launer, LJ , Le Marchand, L , Lee, H , Lee, NR , Bradfield, JP , Lehtimaki, T , Li, H , Li, L , Lieb, W , Lin, X , Lind, L , Linneberg, A , Liu, C-T , Loeffler, M , Bradford, Y , London, B , Lubitz, SA , Lye, SJ , Mackey, DA , Magi, R , Magnusson, PKE , Marcus, GM , Vidal, PM , Martin, NG , Marz, W , Braund, PS , Matsuda, F , McGarrah, RW , McGue, M , McKnight, AJ , Medland, SE , Mellstrom, D , Metspalu, A , Mitchell, BD , Mitchell, P , Mook-Kanamori, DO , Brody, JA , Morris, AD , Mucci, LA , Munroe, PB , Nalls, MA , Nazarian, S , Nelson, AE , Neville, MJ , Newton-Cheh, C , Nielsen, CS , Nothen, MM , Burgdorf, KS , Ohlsson, C , Oldehinkel, AJ , Orozco, L , Pahkala, K , Pajukanta, P , Palmer, CNA , Parra, EJ , Pattaro, C , Pedersen, O , Pennell, Craig E. , Cade, BE , Penninx, BWJH , Perusse, L , Peters, A , Peyser, PA , Porteous, DJ , Posthuma, D , Power, C , Pramstaller, PP , Province, MA , Qi, Q , Cai, H , Qu, J , Rader, DJ , Raitakari, OT , Ralhan, S , Rallidis, LS , Rao, DC , Redline, S , Reilly, DF , Reiner, AP , Rhee, SY , Sakaue, Saori , Cai, Q , Ridker, PM , Rienstra, M , Ripatti, S , Ritchie, MD , Roden, DM , Rosendaal, FR , Rotter, J , Rudan, I , Rutters, F , Sabanayagam, C , Campbell, A , Saleheen, D , Salomaa, V , Samani, NJ , Sanghera, DK , Sattar, N , Schmidt, B , Schmidt, H , Schmidt, R , Schulze, MB , Schunkert, H , Canadas-Garre, M , Scott, LJ , Scott, Rodney J. , Sever, P , Shiroma, EJ , Shoemaker, MB , Shu, X-O , Simonsick, EM , Sims, M , Singh, JR , Singleton, AB , Catamo, E , Sinner, MF , Smith, JG , Snieder, H , Spector, TD , Stampfer, MJ , Stark, KJ , Strachan, DP , t' Hart, LM , Tabara, Y , Tang, H , Chai, J-F , Tardif, J-C , Thanaraj, TA , Timpson, NJ , Tonjes, A , Tremblay, A , Tuomi, T , Tuomilehto, J , Tusie-Luna, M-T , Uitterlinden, AG , van Dam, RM , Chai, X , van der Harst, P , Van der Velde, N , van Duijn, CM , van Schoor, NM , Vitart, V , Volker, U , Vollenweider, P , Volzke, H , Wacher-Rodarte, NH , Walker, M , Chang, L-C , Wang, YX , Wareham, NJ , Watanabe, RM , Watkins, H , Weir, DR , Werge, TM , Widen, E , Wilkens, LR , Willemsen, G , Willett, WC , Chang, Y-C , Wilson, JF , Wong, T-Y , Woo, J-T , Wright, AF , Wu, J-Y , Xu, H , Yajnik, CS , Yokota, M , Yuan, J-M , Zeggini, E , Chen, C-H , Zemel, BS , Zheng, W , Zhu, X , Zmuda, JM , Zonderman, AB , Zwart, J-A , Chasman, D , Cho, YS , Heid, IM , McCarthy, M , Chesi, A , Ng, MCY , O'Donnell, CJ , Rivadeneira, F , Thorsteinsdottir, U , Sun, Y , Tai, ES , Boehnke, M , Deloukas, P , Justice, AE , Lindgren, CM , Graff, Marielisa , Choi, SH , Loos, RJF , Mohlke, KL , North, KE , Stefansson, K , Walters, RG , Winkler, TW , Young, KL , Loh, P-R , Esko, T , Chung, R-H , Assimes, TL , Auton, A , Abecasis, GR , Willer, CJ , Locke, AE , Berndt, S , Lettre, G , Frayling, TM , Okada, Y , Wood, AR , Cocca, M , Visscher, PM , Hirschhorn, JN , Concas, MP , Couture, C , Cuellar-Partida, G , Danning, R , Daw, EW , Degenhard, F , Delgado, GE , Eliasen, Anders U. , Delitala, A , Demirkan, A , Deng, X , Devineni, P , Dietl, A , Dimitriou, M , Dimitrov, L , Dorajoo, R , Ekici, AB , Engmann, JE , Jiang, Yunxuan , Fairhurst-Hunter, Z , Farmaki, A-E , Faul, JD , Fernandez-Lopez, J-C , Forer, L , Francescatto, M , Freitag-Wolf, S , Fuchsberger, C , Galesloot, TE , Gao, Y , Raghavan, Sridharan , Gao, Z , Geller, F , Giannakopoulou, O , Giulianini, F , Gjesing, AP , Goel, A , Gordon, SD , Gorski, M , Grove, J , Guo, X
- Resource Type: journal article
- Date: 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
- Creator: Runtsch, Marah C. , Angiari, Stefano , Mendez, Rui Santalla , Zotta, Alessia , Peace, Christian G. , Walsh, Aoife , Chirillo, Roberta , Hams, Emily , Fallon, Padraic G. , Jayamaran, Ranjith , Dua, Kamal , Brown, Alexandra C. , Hooftman, Alexander , Kim, Richard Y. , Horvat, Jay C. , Hansbro, Philip M. , Wang, C , O'Neill, LAJ , Wadhwa, Ridhima , Zhang, Yanling , Zheng, Yunan , Spina, Joseph S. , Ruzek, Melanie C. , Argiriadi, Maria A. , McGettrick, Anne F.
- Resource Type: journal article
- Date: 2022